Narcolepsy Essays - Sleep Disorders, Narcolepsy, Orexin, Cataplexy

Narcolepsy Narcolepsy is a disease that has been on the receiving end of many jokes in our society. Yet it is a serious and life altering disease that is no laughing matter to the 1,000 in every 2,000 people in the U.S. that have it. I was drawn to this article because a former supervisor that I worked with had this disease. She was prescribed the drug Ritalin. It always impressed me that she could confront an angry client or give a speech without succumbing to the symptoms of her disease. She revealed that her case of narcolepsy wasn't that bad, but without the Ritalin she would just fall asleep anywhere. "The overall incident of narcolepsy is about 10 times that of Lou Gehrig's disease, half that of multiple sclerosis, five times that of cystic fibrosis, and about one quarter that of Parkinson's disease." Narcolepsy is a chronic disease, but not a progressive one. It is a puzzling neurological disorder that causes cataplexy, the loss of skeletal muscle tone without loss of consciousness, and persistent daytime sleepiness. Cataplectic attacks of narcolepsy can be triggered by exceedingly strong emotions such as laughter, embarrassment, anger, and athletic or sexual exertion. In tests on narcoleptic dogs, Emmanuel Mignot of Stanford and his co-workers identified a gene responsible for narcolepsy in dogs. "His research group determined that the dogs carry a mutation in the receptor for a neurotransmitter called hypocretin or orexin." These receptors are missing a critical part, so they can't respond normally to messages they receive. This is a recessive trait in the canines. However, they state that it is unlikely that most human narcoleptics have these mutated genes. Most narcoleptics have no narcoleptic relatives, and the disease does not occur until the second or third decade of life. Also, they have concluded that in 75 percent of the cases in which narcolepsy occurs in an identical twin, the other twin is unaffected. This, they say, indicates that environmental conditions are important in human narcolepsy. What environmental conditions are they? Damage to the hypocretin/orexin system due to environmental factors may mimic the symptoms caused by mutations. They feel that narcolepsy may be an auto-immune disease, in that the body turns against one of its own tissues are cell types. "The next step will be to determine whether the immune systems of narcoleptics are mistakenly targeting the hypocretin/orexin receptors in their own brains as foreign." according to Jerome Siegel. There are no concrete answers at the present time. Just hypotheses. Right now the only thing that science has to offer a narcoleptic is drugs to control their symptoms. For which I am sure that the sufferers of this disease are very grateful. We never seem to care about a disease until it strikes us or a loved one or friend. I'm thankful we have scientists out there who are working on answers to the causes and cures of various diseases, that hopefully, we may never have occasion to know about.

Writing a Sample Essay For Each Sample Application

Writing a Sample Essay For Each Sample ApplicationBefore you decide to write a sample essay for each sample application, you should make sure that you write each sample essay in the exact same way and using the exact same vocabulary. In addition, the phrase you use throughout the writing should be taken literally. For example, if you wrote the sample application in English grammar and you use the phrase 'in line with your practice'.The first hint that you should remember about how to write an essay for each sample application is that it should reflect the personality of the student who will read the application. For example, if you had a student who was very enthusiastic about environmental issues, a sample essay should use an attitude and tone that describe their enthusiasm. If the student is very serious about using a specific product, the writing should reflect this as well.Another hint that you should remember about how to write an essay for each sample application is that the st yle of writing that your student is most comfortable with. For example, if you are writing a sample essay that your student has not written before, you should use a formal style. This means that your student should use proper spelling and grammar.If you are writing an essay for a student who writes very quickly, you should use a conversational style. You should use simple language and not long and complex sentences. You should talk about the things that you want your student to know or learn. Your student will appreciate this style more if they feel comfortable.There are three aspects that you should take into consideration when writing an essay for each sample application. First, the topic of the essay. Second, the tone and flow of the essay. Third, the writing structure and punctuation.The topic of the essay should be one that will interest the student. It is easy to confuse a topic that is too general with a general topic and they are not very good essays. You should base the top ic of the essay on the interest of the student. If you find that the student enjoys writing about wine, but not so much about geography, then it may be time to include a special interest topic into the essay.The tone and flow of the essay should be done using the tone and flow of speech that the student will use. You should be sure that your student understands that their style of writing and their personality should be reflected in the style of writing that you choose. You should also keep in mind that the student's writing is being evaluated so there should be no grammatical errors in sentence structure.As you can see, it is important to take these hints into consideration when writing each individual sample essays. Even if you are writing an essay for each application, make sure that you write each one in the exact same way and using the exact same vocabulary.

IKEA Marketing Case Study Essay Example

IKEA Marketing Case Study Essay Example IKEA Marketing Case Study Paper IKEA Marketing Case Study Paper Burke Case Analysis weaknesses (positioning, weak online sales, etc. ) in the U. S market into a great opportunities. Define the Problem: Adapting to an ever-aging U. S market where the only thing constant, is change. KEA must develop ways to change and position themselves in a way that they are ahead of the power- curve. With companies that have many more locations and convenient one-stop- shopping such as Target and Walter; KEA must develop a competitive market advantage (that spans beyond simply cost and modern product). Furthermore, KEA must overcome the stigma of being a do-it-yourself retailer in order to compete with companies with whom have reputations and a long history of success such as Home Depot. Background of the Situation: KEA has multiple strengths including: A modern image. A green image. A highly efficient operation that is 51 percent self-sufficient. A 7 percent annual growth rate An anti-bureaucratic image that is promulgated by upper management working in hands on Jobs (cashiers, loaders, etc. ) Ahead of the game with a daycare and restaurants to keep customers in the store longer KEA also has several weaknesses: Marketing in primary countries that is not conducive to the U. Gs conservative ways. Average U. S consumer not being the best target for the do-it-yourself approach. Their ways as far as how they market (word of mouth) Kikes sub-par website forces consumers to shop at the nearest location. Not a well trusted name for products such as mattresses Opportunities: Although there are many elderly individuals who do not like the DID approach there are a vast number of young adults, who can be targeted to become lifelong customers. Threats: Losing market-share to larger retailers. More trusted companies following Kikes trend and stealing from the market share Metric to Test Success: KEA targets market segments based on the following: age, lifestyle, the benefit the buyer is seeking, and the income level. For my solution, I believe the metric for success is simply; do over 66% of my college aged students return every 2 to 4 years. Furthermore, does this happen at least twice? An example is when a young adult completes his or her undergrad, do they return to purchase starter furniture(for a first rented apartment or first purchased home) ? Key Issues: High cost of simply adding more brick and mortar locations Even with 9500 different products, customization is still important Solution 1 . ) Simply adding several brick and mortar locations on top of the existing 38 current U. S locations is both costly and a long fix to a problem that may hold a quicker solution. Positives: More locations to operate means larger market to serve (potentially) Would be easier to ship to more places Negatives: High cost of building Time spent is money spent All orders would be shipped from on central distribution center in the Midwest (cost would be the deciding factor of the final location. More focus on countries with a larger market. Easy distribution from a single point Giving away potential buyers and potential customers. Furthermore, some customers you have already acquired and could be life long customers. Solution 3. ) Creating electronic kiosks supplemented by a rep that can travel to large college campuses within a sixty mile radius of college campuses. These Kiosks can feature the same AD benefits of the existing app, such as dimensions and multiple angles. This furniture would be customizable with University specific covers that would not effect that packaging of Kikes already well efficiently cadged, shipped, stored, and distributed products. Orders of a certain cost would then be delivered and assembled free of charge. Can test to see how much customization would really impact U. S consumers. Much more cost effective than building new locations. Targeting customers that may otherwise not purchase furniture due to the extraneous amount of travel Shifting away from the do it yourself stigma by having products assembled on site Potentially creating lifelong customers. Cost of delivery and assembly Liability of delivery and assembly Additional cost of University specific colors and covers may not outweigh the

3 Expert Tips for Tackling the UVA Essay Prompts

3 Expert Tips for Tackling the UVA Essay Prompts SAT / ACT Prep Online Guides and Tips Founded in 1819 by Thomas Jefferson, the University of Virginia boasts impressive academics, competitive sports team, and a long list of notable alumni. Though over 20,000 students attend UVA, the school has an admissions rate of just 30% - meaning you’ll have to work hard if you want to be a Cavalier. One of the best ways to boost your chances of admissions is by writing great UVA essays as part of your application. In this article, we’ll break down what the UVA essay prompts are and how you can write responses to each prompt that will make you stand out. What Are the UVA Supplemental Essay Prompts? In order to apply to UVA, you’ll submit either the Common or Coalition Application. No matter which option you choose, you’ll have to complete the UVA supplement, which includes two essays. Neither of the UVA essays has a hard word count, though the instructions recommend that you write around half a page, or 250 words. For the first UVA supplement essay, you’re required to write a response based on the school within UVA that you’re applying to. For the second UVA supplement essay, you get to choose the topic that resonates most with you. UVA Essay Prompts Here are the UVA essay prompts for 2018-19: Prompt #1 We are looking for passionate students to join our diverse community of scholars, researchers, and artists. Answer the question that corresponds to the school/program to which you are applying in a half page or roughly 250 words. College of Arts and Sciences - What work of art, music, science, mathematics, or literature has surprised, unsettled, or challenged you, and in what way? School of Engineering and Applied Sciences - If you were given funding for a small engineering project that would make everyday life better for one friend or family member, what would you design? School of Architecture - Describe an instance or place where you have been inspired by architecture or design. School of Nursing - School of Nursing applicants may have experience shadowing, volunteering, or working in a health care environment. Tell us about a healthcare-related experience or another significant interaction that deepened your interest in studying Nursing. Kinesiology Program - Discuss experiences that led you to choose the kinesiology major. Prompt #2 Answer one of the following questions in a half page or roughly 250 words. What’s your favorite word and why? We are a community with quirks, both in language and in traditions. Describe one of your quirks and why it is part of who you are. Student self-governance, which encourages student investment and initiative, is a hallmark of the UVA culture. In her fourth year at UVA, Laura Nelson was inspired to create Flash Seminars, one-time classes which facilitate high-energy discussion about thought-provoking topics outside of traditional coursework. If you created a Flash Seminar, what idea would you explore and why? UVA students paint messages on Beta Bridge when they want to share information with our community. What would you paint on Beta Bridge and why is this your message? UVA students are charged with pushing the boundaries of knowledge to serve others and contribute to the common good. Give us an example of how you’ve used what you’ve learned to make a positive impact in another person’s life. UVA Essays, Analyzed Looking for advice on how to write amazing UVA essays? Let’s break down how to answer each prompt. UVA Prompt #1 The instructions are the same for all of the first UVA essays: "We are looking for passionate students to join our diverse community of scholars, researchers, and artists. Answer the question that corresponds to the school/program to which you are applying in a half page or roughly 250 words." Let’s look at how to answer each one. College of Arts and Sciences - What work of art, music, science, mathematics, or literature has surprised, unsettled, or challenged you, and in what way? This prompt gives you an opportunity to examine many different fields. The key is to pick something you’re passionate about. Passion doesn’t always have to be a good thing. You may be passionate about why Pride Prejudice is the worst book ever written. This essay asks about something that has surprised, unsettled, or challenged you - you don’t need to pick your favorites here. Consider picking something that has reframed your perception of the world. Have you read a book that opened your eyes to another culture? Has some fact of science truly blown your mind? Go with something that has shifted how you view and conceptualize the world. Again, it doesn’t have to be in a good way. School of Engineering and Applied Sciences - If you were given funding for a small engineering project that would make everyday life better for one friend or family member, what would you design? This prompt allows you to think out of the box! In order to ace this essay, go small (it says so in the prompt) and personal. You don’t need to dream up a cure for cancer or a new way to bring water to the developing countries. Think about a challenge that faces the ones you love every day - you should pick something that feels real and honest. Don’t try to impress with size and scale here. Instead, make a small, meaningful impact. If you’re able to describe how your project really makes a change, it will be more memorable in the eyes of the admissions committee. School of Architecture - Describe an instance or place where you have been inspired by architecture or design. Inspiration comes in many forms - what’s important for this prompt is to think about what has inspired you, not the masses. In other words, don’t feel like you need to pick the Empire State Building if you weren’t actually inspired by that work. Pick something that was meaningful to you and expand on why it impacted you. You could even pick a small home - something that encouraged you to think of building dwellings that are important for families. Whatever you choose, you should be sincere about your inspiration. Anything that sounds trite will be really obvious to the admissions committee. They’ll read thousands of applications about wanting to make the tallest building in the world - make yours sound different. School of Nursing - School of Nursing applicants may have experience shadowing, volunteering, or working in a health care environment. Tell us about a healthcare-related experience or another significant interaction that deepened your interest in studying Nursing Don’t feel like you need to highlight a huge moment here - rather, focus on something that’s significant to you even if that experience was small! The key to this prompt is to make sure that you’re highlighting something real that happened to you or someone important to you. The more personal you can make the experience, the better. Saying something like â€Å"I want to solve cancer for everyone† is less impactful than saying that you have seen firsthand how cancer affected your grandmother. Nursing is a personal profession - lean into that for this essay. Kinesiology Program - Discuss experiences that led you to choose the kinesiology major. For this prompt, focus on one or two experiences and discuss them in detail. Don’t give an entire overview of your history - describing something more fully will resonate more than trying to cram a lot of experiences into a relatively short essay. Be honest about what drove you to kinesiology - don’t write what you think the admissions committee wants to hear. Write what’s true for you. UVA Prompt #2: The instructions are the same for all of the second round of UVA prompts: "Answer one of the following questions in a half page or roughly 250 words." You only need to pick one of these questions to answer. What’s your favorite word and why? With a prompt like this, it can be tempting to want to impress the admissions committee with your knowledge of esoteric vocabulary. Don’t go that route, unless you have a true connection to a strange, rarely used word. Pick a word that’s meaningful to you - something that’s very specific to you. The key here isn’t to pick the most interesting word, it’s to have the most meaningful and memorable experience to back it up. If â€Å"family† is really important to you, you need to have a good reason - simply saying you love your parents isn’t enough. Focus on the â€Å"why† rather than the word and you’ll be on the right track. We are a community with quirks, both in language and in traditions. Describe one of your quirks and why it is part of who you are. This prompt offers you a chance to show off a side of yourself that the rest of your application doesn’t highlight. Take advantage of it! Do you have a passion for collecting Minnie Mouse figurines? Do you have to run four miles every single morning? Do you stop everything you’re doing whenever the Red Sox are playing? Do your parents always make fun of you for pronouncing a word strangely? Whatever your quirk is, now’s the time to celebrate it! Write freely and without embarrassment - a quirk is a quirk! It’s not supposed to seem normal. The admissions committee won’t judge you for your quirk. They want to learn the interesting parts about your personality. Student self-governance, which encourages student investment and initiative, is a hallmark of the UVA culture. In her fourth year at UVA, Laura Nelson was inspired to create Flash Seminars, one-time classes which facilitate high-energy discussion about thought-provoking topics outside of traditional coursework. If you created a Flash Seminar, what idea would you explore and why? The topic you choose doesn’t have to be high-brow or exceedingly academic - rather, you need to pick a topic that’ll inspire thought-provoking conversations. If that conversation is, â€Å"What does Kim Kardashian say about the future of advertising?† that’s fine! As long as the topic is important to you. As with the other prompts, the word â€Å"why† is the most important of this prompt. You need to have a strong reason for wanting to explore this topic. If you want to talk about Kim Kardashian, that’s cool - as long as you can indicate why this is a topic worthy of discussion. UVA students paint messages on Beta Bridge when they want to share information with our community. What would you paint on Beta Bridge and why is this your message? As with the other prompts, the â€Å"why† is the most important part of this question. Whatever message you land on, make sure you have a good reason for it. Avoid trite or cliched phrases, like â€Å"Be the change you wish to see in the world.† The admissions committee will have seen thousands of these - and those words are probably already written on Beta Bridge. What do you have to say? What message is personal to you? What lesson have you learned that you specifically can communicate? UVA students are charged with pushing the boundaries of knowledge to serve others and contribute to the common good. Give us an example of how you’ve used what you’ve learned to make a positive impact in another person’s life. First and foremost: don’t make something up here. Don’t say that you spent months devoted to helping a family whose father was suffering from cancer if that’s just not true. While this prompt does encourage you to share how you’ve served people, it’s not a contest. You don’t have to have the grandest and most impressive example of selflessness that the committee’s ever read. What you do need to have is sincerity - talk about how you helped someone and why that experience was so impactful. Explain what led you to help and reflect on how UVA might inspire similar feelings of service in you. How to Write UVA Essays Here are some general tips for how to write UVA essays that will wow the committee. #1: Be You Your UVA supplement essay is a chance to show the admissions committee who you are. Take that opportunity to flesh yourself out. You’re not simply a collection of A’s and B’s printed on a transcript. You’re a real person! Show that in your UVA essays. #2: Feedback Is Cool; Plagiarism Is Not It can be tempting to bounce essay ideas off your peers, parents, and teachers. That’s fine! But don’t rely on them too heavily. Your work should be your own - from the ideas to the execution. There’s a fine line between receiving helpful feedback and using that feedback in a way that misrepresents your work and ability. Seek out help, but know that you have the first and final say. #3: Play With Form Your UVA essays don't have to follow the traditional five paragraph structure. UVA encourages you to play with form. That means you can submit a poem, if you want! Take advantage of the freedom from structure to write in a way that feels authentic to you. If that means starting every sentence with the letter â€Å"E†, then go for it! As long as your work is well-written and engaging, the form doesn’t matter. What’s Next? There are over 5,000 colleges in the United States- how can you possibly decide which to apply to? Using a college finder tool can help you sort through your options and find your ideal school without having to tour every single campus. Once you've decided on some colleges or universities that you're interested in attending, our guide will help you narrow down your list to safeties, matches, and reach school. Still not sure what you're looking for in a college?Read our articles on whether you should go to a school close to home and whether you should attend a large or small college. Want to write the perfect college application essay? Get professional help from PrepScholar. Your dedicated PrepScholar Admissions counselor will craft your perfect college essay, from the ground up. We'll learn your background and interests, brainstorm essay topics, and walk you through the essay drafting process, step-by-step. At the end, you'll have a unique essay that you'll proudly submit to your top choice colleges. Don't leave your college application to chance. Find out more about PrepScholar Admissions now:

Research Method in E-Logistics and Supply Chain Management Essay

Research Method in E-Logistics and Supply Chain Management - Essay Example This study focuses on a specific aspect of commerce: the supply chain management; emphasis is given on the risk involved in international shipping. Appropriate methods of research have been used in order to identify and explain the various aspects of the specific aspect of commerce. The literature review and the empirical research developed for this study have led to the assumption that risk can be related with all parts of commercial activities; the limitation of this risk is a challenging target, usually depended on the tools available but also on the experience/ capabilities of the persons involved. According to the report findings the use of existing theoretical framework has been proved particularly helpful for the effective handling of risk in commerce; unexpected problems may always appear leading to the decrease of effectiveness of the relevant theories and policies. The role of the persons that involve in the various phases of this activity, i.e. international shipping, is crucial for the limitation of risk; the state also has an important role to the control of the risk involved in international shipping but this role is usually depended on its power to enforce the relevant legal rules. The expansion of globalization has caused the alteration of business priorities worldwide; having to face the increased competition firms in all industrial sectors have been obliged to adopt innovative practices and to monitor all their activities making sure that they will be able to keep their position in the local or the international market.

Quantitative research Essay Example | Topics and Well Written Essays - 1000 words

Quantitative research - Essay Example On the other hand, the problem of the study is that persistent nursing shortages, in addition to, the worry about the quality of current health care emphasize the vital need to employ and retain a cadre of expert nurses in the nation’s hospitals. The researchers carried out an extensive literature review on the literature that supports the problem of the study. In addition, the study has mainly used primary sources, which provide evidence-based information for the investigation (Polit and Beck, 2008). However, the researcher used a number of information resources that are not up to date with some written 22 years before the time of the study. The researchers should have used latest literature, probably those published within 7 years or so. The literature review also provides a state-of-the-art blending of evidence with regard to the research problem, and it provides a substantial foundation for this study. In the study, the researchers have included a number of concepts, which they have adequately defined conceptually. The researchers have also included a conceptual framework, which is appropriate because it clearly defines the concepts of the study and the professional practice model that is suitable for the study. Although the researchers have not provided a conceptual map, it is justified because it could have served the purpose of the conceptual framework. The study included the following a set of three questions, which are explicitly stated. The questions sought to find out the baseline level of job satisfaction by nurses in a pediatric hospital with a conventional, hierarchical nursing administrative structure before the realization of an innovative professional practice model. It also sought to identify changes in job satisfaction that are associated with the execution of a fresh professional practice model whose emphasis is on participatory governance. The other question wanted to find out how the level of job satisfaction changes from the time o f submitting the Magnet recognition application to a year post submission in the chosen case. These questions are correctly worded with logical specification of the key variables and the study population. In addition, the questions are in tandem with the literature that the researchers reviewed and the conceptual framework that they provided. The researcher included a single hypothesis, which stated that the process of transforming the model of nursing control to participatory from top-down in order to attain Magnet recognition might be hectic and would be related with decreases in nurses’ satisfaction at work. The hypothesis is also suitable for the study because it clearly specifies key variables and it is consistent with the conceptual framework and the literature review (Polit and Beck, 2008). The study was cross-sectional, and it examined job satisfaction in a private pediatric, 282-bed hospital. The researcher conducted the study before, during, and directly after the a pplication for and achievement of a Magnet hospital position. It was during the time when nursing administrators, staff nurses, hospital nursing administrators, and nurse managers in cooperation developed a formal collective governance

Lithuanian Economy Essay -- Economy, Low Cost Transactions

Introduction In my research project I will be talking about the history of Lithuanian economy and how it had changed since the country became independent and took a place as a member of a European Union. In my work you will be able to see different points of view of being a citizen of the EU and the problems the countries are facing to get this membership. Lithuania’s membership in the European Union would be impossible without the public assent and support. This support was made most explicit during the referendum on the membership in the European Union on 10-11 May 2003, when 91.07% of those participating (the turnout was 63.37%) approved of Lithuania’s accession to the EU. (Euro 2007) The Lithuanian economy has reached high growth rates in the last decade as it entered the European Union together with other Baltic states. The government went in for a flat tax; the unemployment rates were fairly low until a recent recession began. Lithuania has been changing over from the communist planned economy in the Soviet Union since; it got independence that is 1990. Although Lithuania suffered a lot from U.S.S.R. it still kept a good relationship and nowadays Russia is one of the main traders with Lithuania. However, it faced its own economic and financial crisis in 1999, partly due to the 1998 Russian financial crisis. Since then Lithuania had changed its views towards the European Union; it became a member of EU on 1st May 2004. (Wikipedia, 2009) According to the survey of market participants in January and February 2004, the Lithuanian economy grew rapidly. The financial situation of Lithuanian companies improved and the costs of borrowing declined in 2003. At that time GDP in Lithuania reached over 10%. Economic growt... ...e accurate. As I was doing some research for this project I found that the government did this kind of survey in Lithuania, to find out what was general public opinion before Lithuania became EU member. In 2003 over 91% did the survey and almost 64% agreed with Lithuania going for EU membership. The same survey was repeated few years later. What did not surprise me was that people opinion changed after accession to EU. In the survey done in 2008 over 75% of the Lithuanians agreed that Lithuania has benefited from EU membership. In my research plan I would like to do this kind of questionnaire where I could see how the people agree and disagree with membership of EU. I would question them on their perceptions of how membership has affected their country. Also what changes they would like to see especially in areas, which they see as problematic.